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Breast-conserving surgery with or without irradiation in early breast cancer.

22 March 2023
Randomized clinical trials Breast
Kunkler IH, Williams LJ, Jack WJL, Cameron DA, Dixon JM.

N Engl J Med 2023; 388: 585-594.

The study included 1326 women aged 65 or over with ER+ve breast cancer completely excised. After a median follow-up of 9.1 years, the addition of whole breast radiotherapy reduced the risk of local recurrence (0.9 versus 9.5 per cent, P<0.0001), but did not affect overall survival: 80.7 versus 80.8 per cent, respectively.

Comment: Very helpful study that enables women to make a choice.

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